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UEFA Champions league winners, Real Madrid Tuesday night crushed APOEL Nicosia 6-0 in Cyprus with goals from Cristiano Ronaldo and Karem Benzema scoring twice.
Luka Modric and Nacho were also on the score-sheet.
Liverpool threw away a three-goal lead to draw 3-3 at Sevilla.
Raheem Sterling struck late, as Manchester City beat Feyernoord 1-0 at the Etihad, while Napoli thrashed Shakhtar Donetsk 3-0 in Italy. Tottenham Hotspur fought back from a goal down, to win 2-1 against Borussia Dortmund at the Signal Iduna Park.
Spartak Moscow drew 1-1 with Maribor, while RB Leipzig defeated Monaco 4-1 in France.
Besiktas had earlier qualified for the roudnof 16, following a 1-1 draw at home with FC Porto
